Suzuki Coupling
Suzuki coupling is a widely used cross coupling reaction between an organohalide and an organoborinic acid. The reaction is typically catalysed by a Pd-based catalyst and runs under mild conditions. A wide variety of solvents can be used including water and aromatic solvents such as toluene and ethers such as THF and Me-THF. This reaction has found wide use in both the agrochemical and pharmaceutical areas due to its broad capability.
The Suzuki reaction is widely used to synthesize polyolefins, styrenes, and substituted biphenyls.
Suzuki coupling can be the reaction of choice for production of pharmaceutical intermediates and active agrochemicals and other fine and specialty chemicals.